Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Aug 1;129(15):2881-6.
doi: 10.1242/jcs.186205.

The cytotoxic T lymphocyte immune synapse at a glance

Nele M G Dieckmann  1 , Gordon L Frazer  1 , Yukako Asano  1 , Jane C Stinchcombe  1 , Gillian M Griffiths  2
Affiliations
Review

The cytotoxic T lymphocyte immune synapse at a glance

Nele M G Dieckmann et al. J Cell Sci. .

Abstract

The immune synapse provides an important structure for communication with immune cells. Studies on immune synapses formed by cytotoxic T lymphocytes (CTLs) highlight the dynamic changes and specialised mechanisms required to facilitate focal signalling and polarised secretion in immune cells. In this Cell Science at a Glance article and the accompanying poster, we illustrate the different steps that reveal the specialised mechanisms used to focus secretion at the CTL immune synapse and allow CTLs to be such efficient and precise serial killers.

Keywords: Cytotoxic T lymphocyte; Immune synapse; Secretion.

PubMed Disclaimer

Publication types

Substances

LinkOut - more resources