Critical Role of Iron in Epoetin Alfa Treatment of Chemotherapy-Associated Anemia
- PMID: 27507872
- PMCID: PMC5477928
- DOI: 10.1200/JCO.2016.67.7377
Critical Role of Iron in Epoetin Alfa Treatment of Chemotherapy-Associated Anemia
Comment in
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Reply to T. Hasegawa et al and I. Gross et al.J Clin Oncol. 2016 Nov 1;34(31):3820-3821. doi: 10.1200/JCO.2016.68.7681. J Clin Oncol. 2016. PMID: 27507880 Free PMC article. No abstract available.
Comment on
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A Randomized, Open-Label, Multicenter, Phase III Study of Epoetin Alfa Versus Best Standard of Care in Anemic Patients With Metastatic Breast Cancer Receiving Standard Chemotherapy.J Clin Oncol. 2016 Apr 10;34(11):1197-207. doi: 10.1200/JCO.2015.63.5649. Epub 2016 Feb 8. J Clin Oncol. 2016. PMID: 26858335 Clinical Trial.
References
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- Loo M, Beguin Y. The effect of recombinant human erythropoietin on platelet counts is strongly modulated by the adequacy of iron supply. Blood. 1999;93:3286–3293. - PubMed
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- Auerbach M, Ballard H, Trout JR, et al. Intravenous iron optimizes the response to recombinant human erythropoietin in cancer patients with chemotherapy-related anemia: A multicenter, open-label, randomized trial. J Clin Oncol. 2004;22:1301–1307. - PubMed
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