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Case Reports
. 2016 Sep;68(3):374-6.
doi: 10.1007/s12070-015-0959-8. Epub 2015 Dec 22.

Metastatic Renal Cell Carcinoma Presenting as Nasal Mass: Case Report and Review of Literature

Ritesh Mahajan  1 , Nagaraj Mayappa  2 , V Prashanth  2
Affiliations
Case Reports

Metastatic Renal Cell Carcinoma Presenting as Nasal Mass: Case Report and Review of Literature

Ritesh Mahajan et al. Indian J Otolaryngol Head Neck Surg. 2016 Sep.

Abstract

Sinonasal neoplasms are rare and exceptional site for metastatic tumours and comprising <3 % of all malignant aerodigestive tumours and <1 % of all malignancies. Renal cell carcinoma is known to metastasise to the most unusual sites, the sinonasal region being one of them. We here by present a case of 60 year old male patient who presented with epistaxis and nasal obstruction. Clinical examination and CT scan revealed a tumour in the right nasal cavity and maxillary sinus. The presence of primary renal cell carcinoma was recognized only after surgical removal of metastatic tumour. Very few reports have been presented in literature of metastatic renal cell carcinoma in the sinonasal region. We present this case to document its occurrence; highlight the rarity, presentation and difficulties in diagnosis and treatment along with review of literature.

Keywords: Epistaxis; Metastasis; Renal cell carcinoma (RCC); Sinonasal region.

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Figures

Fig. 1
Fig. 1
CECT images: Plain CT image showing involvement of right nasal cavity and maxillary sinus
Fig. 2
Fig. 2
CECT images: CT image with contrast showing a heterogeneously enhancing mass
Fig. 3
Fig. 3
Histopathological images: Photomicrograph showing immunohistochemical stain for CK in metastatic RCC (40×)
Fig. 4
Fig. 4
Histopathological images: Photomicrograph showing immunohistochemical stain for Vim in metastatic RCC (10×)
See this image and copyright information in PMC

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