Human leukocyte antigen (HLA)-binding epitopes dataset for the newly identified T-cell antigens of Mycobacterium immunogenum
- PMID: 27508266
- PMCID: PMC4969084
- DOI: 10.1016/j.dib.2016.06.045
Human leukocyte antigen (HLA)-binding epitopes dataset for the newly identified T-cell antigens of Mycobacterium immunogenum
Abstract
The dataset described herein is related to our article entitled "T-cell antigens of Mycobacterium immunogenum (MI), an etiological agent of occupational hypersensitivity pneumonitis'' (Chandra and Yadav, 2016) [1]. The data include in silico-predicted T-cell epitopes of the T-cell antigens AgA and AgD of MI predicted to bind to HLA-I or HLA-II alleles. Data on two reference T-cell antigens ESAT-6 and CFP-10 of Mycobacterium tuberculosis H37Rv are included for comparison. The data for each antigen include the predicted epitope׳s amino acid sequence, its first amino acid position, and its ability to bind HLA-I or HLA-II allele(s).
Keywords: HLA-I; HLA-II; Hypersensitivity pneumonitis; Immunoinformatics; Mycobacterium immunogenum; Mycobacterium tuberculosis; T-cell antigen; T-cell epitopes.
References
-
- Chandra H., Yadav J.S. T-cell antigens of Mycobacterium immunogenum, an etiological agent of occupational hypersensitivity pneumonitis. Mol. Immunol. 2016;75:168–177. - PubMed
-
- Rosenman K. Occupational diseases in individuals exposed to metal working fluids. Curr. Opin. Allergy. Clin. Immunol. 2015;15:131–136. - PubMed
-
- Gupta M.K., Subramanian V., Yadav J.S. Immunoproteomic identification of secretory and subcellular protein antigens and functional evaluation of the secretome fraction of Mycobacteriumimmunogenum, a newly recognized species of the Mycobacteriumchelonae- Mycobacteriumabscessus group. J. Proteome Res. 2009;8:2319–2330. - PubMed
-
- Chandra H., Lockey J., Yadav J.S. Novel antigens of Mycobacteriumimmunogenum relevant in serodiagnosis of occupational hypersensitivity pneumonitis in machinists. Ann. Allergy Asthma Immunol. 2015;114:525–526. - PubMed
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials
Miscellaneous
