[Endometrial estradiol and progesterone receptors in women with various clinical forms of luteal insufficiency]

Abstract

Changes in uterine estradiol and progesterone receptor content in patients with luteal insufficiency (the insufficient luteal phase/ILP/ syndrome developing in the presence of tubal and uterine inflammations, hyperandrogenism or insignificantly increased prolactin level were described. The level of steroid receptors is correlated to blood levels of the respective hormones throughout the cycle. It is suggested that changes in sex steroid receptors are secondary to disorders of progesterone and estradiol secretion in cases of the ILP syndrome developing in the presence of uterine and tubal inflammations, and in patients with increased blood prolactin. In hyperandrogenic patients with the ILP syndrome, nuclear progesterone receptors night possibly be inadequate.