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. 2016 Aug 11;20(1):250.
doi: 10.1186/s13054-016-1435-x.

Saline versus balanced solutions: are clinical trials comparing two crystalloid solutions really needed?

Jean-Louis Vincent  1 , Daniel De Backer  2
Affiliations

Saline versus balanced solutions: are clinical trials comparing two crystalloid solutions really needed?

Jean-Louis Vincent et al. Crit Care. .
No abstract available

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Figures

Fig. 1
Fig. 1
The likely results from a hypothetical randomized clinical trial (RCT) comparing a saline solution with a balanced solution in critically ill patients. Scenario A: saline solutions are discontinued as soon as hyperchloremia appears, thus preventing the harmful effects of a further increase in chloremia and there will likely be no difference in outcomes in the two arms. Scenario B: the administration of saline solutions is continued despite the development of hyperchloremia and the saline group will have worse outcomes than the balanced group
See this image and copyright information in PMC

References

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