Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2014 Mar;7(1):4-7.
doi: 10.1177/1753495X13502785. Epub 2013 Nov 29.

Update on vitamin D: More than just a nutrient

Christopher White  1
Affiliations
Review

Update on vitamin D: More than just a nutrient

Christopher White. Obstet Med. 2014 Mar.

Abstract

An increasing number of pregnancy complications have been ascribed or at least associated with vitamin D deficiency. Vitamin D has undergone a metamorphosis from nutrient to hormone and more recently has been recognised to have broader biological relevance. This includes potential immunogenic, oncogenic and metabolic actions. This review outlines the roles of vitamin D, the problems in accurate measurement and determining normal ranges and how this is important in an understanding of vitamin D in normal and abnormal pregnancy.

Keywords: Pregnancy; reference values; vitamin D.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
1,25(OH)2D3 levels and calcium metabolism in pregnancy.
Figure 2.
Figure 2.
Various levels of serum 25OHD (ng/ml) at which serum PTH (pg/ml) plateaus and/or is maximally suppressed. (Reproduced with permission JCEM.)
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Rajakumar K. Vitamin D, cod-liver oil, sunlight, and rickets: a historical perspective. Pediatrics 2003; 112: e132–e135. - PubMed
    1. Lightwood R. Hypercalcaemia in infants and vitamin D. BMJ 1956; 2: 149–149.
    1. Fraser DR, Kodicek E. Unique biosynthesis by kidney of a biologically active vitamin D metabolite. Nature 1970; 228: 764–766. - PubMed
    1. Holick MF, Schnoes HK, DeLuca HF, et al. Isolation and identification of 1,25-dihydroxycholecalciferol. A metabolite of vitamin D active in the intestine. Biochemistry 1971; 10: 2799–2804. - PubMed
    1. Jones G, Strugnell SA, DeLuca HF. Current understanding of the molecular actions of vitamin D. Physiol Rev 1998; 78: 1193–1231. - PubMed

LinkOut - more resources