Polyamines: Small Molecules with a Big Role in Promoting Virus Infection
- PMID: 27512896
- DOI: 10.1016/j.chom.2016.07.012
Polyamines: Small Molecules with a Big Role in Promoting Virus Infection
Abstract
Polyamines play important roles in a range of cellular processes. In this issue of Cell Host & Microbe, Mounce et al. (2016) link polyamine metabolism to the interferon response and demonstrate proviral effects for polyamines. The study points to the pathway as a potential novel pan-viral therapeutic target.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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Interferon-Induced Spermidine-Spermine Acetyltransferase and Polyamine Depletion Restrict Zika and Chikungunya Viruses.Cell Host Microbe. 2016 Aug 10;20(2):167-77. doi: 10.1016/j.chom.2016.06.011. Epub 2016 Jul 14. Cell Host Microbe. 2016. PMID: 27427208
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