When Mr. Fap Meets the Gals
- PMID: 27512897
- DOI: 10.1016/j.chom.2016.07.013
When Mr. Fap Meets the Gals
Abstract
Fusobacteria are found to be overrepresented in the colorectal tumor microenvironment. In this issue of Cell Host & Microbe, Abed et al. (2016) describe a novel homing mechanism by which fusobacteria localize to tumors by recognizing a host polysaccharide (Gal-GalNAc) on cancer cells using a fusobacterial lectin, Fap2.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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Fap2 Mediates Fusobacterium nucleatum Colorectal Adenocarcinoma Enrichment by Binding to Tumor-Expressed Gal-GalNAc.Cell Host Microbe. 2016 Aug 10;20(2):215-25. doi: 10.1016/j.chom.2016.07.006. Cell Host Microbe. 2016. PMID: 27512904 Free PMC article.
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