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Clinical Trial
. 2016 Oct;17(10):939-947.
doi: 10.1097/PCC.0000000000000918.

Utilizing a Collaborative Learning Model to Promote Early Extubation Following Infant Heart Surgery

William T Mahle  1 , Susan C Nicolson, Danielle Hollenbeck-Pringle, Michael G Gaies, Madolin K Witte, Eva K Lee, Michelle Goldsworthy, Paul C Stark, Kristin M Burns, Mark A Scheurer, David S Cooper, Ravi Thiagarajan, V Ben Sivarajan, Steven D Colan, Marcus S Schamberger, Lara S Shekerdemian; Pediatric Heart Network Investigators
Affiliations
Clinical Trial

Utilizing a Collaborative Learning Model to Promote Early Extubation Following Infant Heart Surgery

William T Mahle et al. Pediatr Crit Care Med. 2016 Oct.

Erratum in

Abstract

Objective: To determine whether a collaborative learning strategy-derived clinical practice guideline can reduce the duration of endotracheal intubation following infant heart surgery.

Design: Prospective and retrospective data collected from the Pediatric Heart Network in the 12 months pre- and post-clinical practice guideline implementation at the four sites participating in the collaborative (active sites) compared with data from five Pediatric Heart Network centers not participating in collaborative learning (control sites).

Setting: Ten children's hospitals.

Patients: Data were collected for infants following two-index operations: 1) repair of isolated coarctation of the aorta (birth to 365 d) and 2) repair of tetralogy of Fallot (29-365 d). There were 240 subjects eligible for the clinical practice guideline at active sites and 259 subjects at control sites.

Interventions: Development and application of early extubation clinical practice guideline.

Measurements and main results: After clinical practice guideline implementation, the rate of early extubation at active sites increased significantly from 11.7% to 66.9% (p < 0.001) with no increase in reintubation rate. The median duration of postoperative intubation among active sites decreased from 21.2 to 4.5 hours (p < 0.001). No statistically significant change in early extubation rates was found in the control sites 11.7% to 13.7% (p = 0.63). At active sites, clinical practice guideline implementation had no statistically significant impact on median ICU length of stay (71.9 hr pre- vs 69.2 hr postimplementation; p = 0.29) for the entire cohort. There was a trend toward shorter ICU length of stay in the tetralogy of Fallot subgroup (71.6 hr pre- vs 54.2 hr postimplementation, p = 0.068).

Conclusions: A collaborative learning strategy designed clinical practice guideline significantly increased the rate of early extubation with no change in the rate of reintubation. The early extubation clinical practice guideline did not significantly change postoperative ICU length of stay.

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Figures

Figure 1
Figure 1
Scheme of the Study Design (PHN = Pediatric Heart Network; CPG = clinical practice guideline).
Figure 2
Figure 2
Interrupted Time Series Analyses of Early Extubation Rates at Active and Control Sites
See this image and copyright information in PMC

Comment in

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