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Comparative Study
. 2017 Nov;54(6):734-738.
doi: 10.1597/16-090. Epub 2016 Aug 12.

Sleep Outcomes in Children With Single-Suture Craniosynostosis Compared With Unaffected Controls

Baiyang Sun, Yona K Cloonan, Brent R Collett, Matthew L Speltz
Comparative Study

Sleep Outcomes in Children With Single-Suture Craniosynostosis Compared With Unaffected Controls

Baiyang Sun et al. Cleft Palate Craniofac J. 2017 Nov.

Abstract

Objective: To compare risk for sleep-disordered breathing between children with and without single-suture craniosynostosis.

Participants: A total of 184 children with single-suture craniosynostosis and 184 controls.

Main outcome measures: Parent reported sleep-disordered breathing-related symptoms.

Results: Current sleep problems were reported in 19% of patients with single-suture craniosynostosis and 14% of controls (adjusted odds ratio = 1.6; 95% CI, 0.9 to 2.8). Ever having sleep problems was reported in 25% and 23% of cases and controls, respectively (adjusted odds ratio = 1.2; 95% CI, 0.7 to 1.9). Overall, snoring was statistically associated with single-suture craniosynostosis (P = .01) and was more often reported as 2+ nights per week (versus never) in patients with single-suture craniosynostosis (13%) than in controls (4%) (adjusted odds ratio = 3.5; 95% CI, 1.5 to 8.2).

Conclusions: Though preliminary, increased presence of snoring during sleep in children with single-suture craniosynostosis compared with controls suggests that children with isolated single-suture craniosynostosis may be at increased risk for sleep-disordered breathing. Further study using standardized assessments of sleep-disordered breathing is needed.

Keywords: craniofacial abnormalities; craniosynostoses; sleep apnea syndromes; sleep disorders; child.

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