Kidney Macrophages: Unique Position Solves a Complex Problem
- PMID: 27518559
- DOI: 10.1016/j.cell.2016.07.047
Kidney Macrophages: Unique Position Solves a Complex Problem
Abstract
Immune complex-mediated diseases, such as systemic lupus erythematosus, commonly affect the kidney and determine disease prognosis. Stamatiades et al. now propose a kidney-specific mechanism for trans-endothelial transport of small immune complexes that activate strategically positioned tissue resident macrophages.
Copyright © 2016 Elsevier Inc. All rights reserved.
Comment on
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Immune Monitoring of Trans-endothelial Transport by Kidney-Resident Macrophages.Cell. 2016 Aug 11;166(4):991-1003. doi: 10.1016/j.cell.2016.06.058. Epub 2016 Jul 28. Cell. 2016. PMID: 27477514 Free PMC article.
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