Executive Summary: Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society

Andre C Kalil¹, Mark L Metersky², Michael Klompas³, John Muscedere⁴, Daniel A Sweeney⁵, Lucy B Palmer⁶, Lena M Napolitano⁷, Naomi P O'Grady⁸, John G Bartlett⁹, Jordi Carratalà¹⁰, Ali A El Solh¹¹, Santiago Ewig¹², Paul D Fey¹³, Thomas M File Jr¹⁴, Marcos I Restrepo¹⁵, Jason A Roberts¹⁶, Grant W Waterer¹⁷, Peggy Cruse¹⁸, Shandra L Knight¹⁸, Jan L Brozek¹⁹

Affiliations

¹ Department of Internal Medicine, Division of Infectious Diseases, University of Nebraska Medical Center, Omaha.
² Division of Pulmonary and Critical Care Medicine, University of Connecticut School of Medicine, Farmington.
³ Brigham and Women's Hospital and Harvard Medical School Harvard Pilgrim Health Care Institute, Boston, Massachusetts.
⁴ Department of Medicine, Critical Care Program, Queens University, Kingston, Ontario, Canada.
⁵ Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego.
⁶ Department of Medicine, Division of Pulmonary Critical Care and Sleep Medicine, State University of New York at Stony Brook.
⁷ Department of Surgery, Division of Trauma, Critical Care and Emergency Surgery, University of Michigan, Ann Arbor.
⁸ Department of Critical Care Medicine, National Institutes of Health, Bethesda.
⁹ Johns Hopkins University School of Medicine, Baltimore, Maryland.
¹⁰ Department of Infectious Diseases, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute, Spanish Network for Research in Infectious Diseases, University of Barcelona, Spain.
¹¹ Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University at Buffalo, Veterans Affairs Western New York Healthcare System, New York.
¹² Thoraxzentrum Ruhrgebiet, Department of Respiratory and Infectious Diseases, EVK Herne and Augusta-Kranken-Anstalt Bochum, Germany.
¹³ Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha.
¹⁴ Summa Health System, Akron, Ohio.
¹⁵ Department of Medicine, Division of Pulmonary and Critical Care Medicine, South Texas Veterans Health Care System and University of Texas Health Science Center at San Antonio.
¹⁶ Burns, Trauma and Critical Care Research Centre, The University of Queensland Royal Brisbane and Women's Hospital, Queensland.
¹⁷ School of Medicine and Pharmacology, University of Western Australia, Perth, Australia.
¹⁸ Library and Knowledge Services, National Jewish Health, Denver, Colorado.
¹⁹ Department of Clinical Epidemiology and Biostatistics and Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

PMID: 27521441
PMCID: PMC4981763
DOI: 10.1093/cid/ciw504

Executive Summary: Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society

Andre C Kalil et al. Clin Infect Dis. 2016.

. 2016 Sep 1;63(5):575-82.

doi: 10.1093/cid/ciw504.

Authors

Affiliations

¹ Department of Internal Medicine, Division of Infectious Diseases, University of Nebraska Medical Center, Omaha.
² Division of Pulmonary and Critical Care Medicine, University of Connecticut School of Medicine, Farmington.
³ Brigham and Women's Hospital and Harvard Medical School Harvard Pilgrim Health Care Institute, Boston, Massachusetts.
⁴ Department of Medicine, Critical Care Program, Queens University, Kingston, Ontario, Canada.
⁵ Division of Pulmonary, Critical Care and Sleep Medicine, University of California, San Diego.
⁶ Department of Medicine, Division of Pulmonary Critical Care and Sleep Medicine, State University of New York at Stony Brook.
⁷ Department of Surgery, Division of Trauma, Critical Care and Emergency Surgery, University of Michigan, Ann Arbor.
⁸ Department of Critical Care Medicine, National Institutes of Health, Bethesda.
⁹ Johns Hopkins University School of Medicine, Baltimore, Maryland.
¹⁰ Department of Infectious Diseases, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute, Spanish Network for Research in Infectious Diseases, University of Barcelona, Spain.
¹¹ Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, University at Buffalo, Veterans Affairs Western New York Healthcare System, New York.
¹² Thoraxzentrum Ruhrgebiet, Department of Respiratory and Infectious Diseases, EVK Herne and Augusta-Kranken-Anstalt Bochum, Germany.
¹³ Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha.
¹⁴ Summa Health System, Akron, Ohio.
¹⁵ Department of Medicine, Division of Pulmonary and Critical Care Medicine, South Texas Veterans Health Care System and University of Texas Health Science Center at San Antonio.
¹⁶ Burns, Trauma and Critical Care Research Centre, The University of Queensland Royal Brisbane and Women's Hospital, Queensland.
¹⁷ School of Medicine and Pharmacology, University of Western Australia, Perth, Australia.
¹⁸ Library and Knowledge Services, National Jewish Health, Denver, Colorado.
¹⁹ Department of Clinical Epidemiology and Biostatistics and Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

PMID: 27521441
PMCID: PMC4981763
DOI: 10.1093/cid/ciw504

Erratum in

Erratum.
[No authors listed] [No authors listed] Clin Infect Dis. 2017 May 1;64(9):1298. doi: 10.1093/cid/ciw798. Clin Infect Dis. 2017. PMID: 28168308 Free PMC article. No abstract available.
Erratum.
[No authors listed] [No authors listed] Clin Infect Dis. 2017 Oct 1;65(7):1251. doi: 10.1093/cid/cix586. Clin Infect Dis. 2017. PMID: 30060023 Free PMC article. No abstract available.

Abstract

It is important to realize that guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment with respect to particular patients or special clinical situations. IDSA considers adherence to these guidelines to be voluntary, with the ultimate determination regarding their application to be made by the physician in the light of each patient's individual circumstances.These guidelines are intended for use by healthcare professionals who care for patients at risk for hospital-acquired pneumonia (HAP) and ventilator-associated pneumonia (VAP), including specialists in infectious diseases, pulmonary diseases, critical care, and surgeons, anesthesiologists, hospitalists, and any clinicians and healthcare providers caring for hospitalized patients with nosocomial pneumonia. The panel's recommendations for the diagnosis and treatment of HAP and VAP are based upon evidence derived from topic-specific systematic literature reviews.

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Comment in

Management of Adults with Hospital-acquired and Ventilator-associated Pneumonia.
Erb CT, Patel B, Orr JE, Bice T, Richards JB, Metersky ML, Wilson KC, Thomson CC. Erb CT, et al. Ann Am Thorac Soc. 2016 Dec;13(12):2258-2260. doi: 10.1513/AnnalsATS.201608-641CME. Ann Am Thorac Soc. 2016. PMID: 27925784 No abstract available.

References

1. American Thoracic Society (ATS) and Infectious Diseases Society of America (IDSA). Guidelines for the management of adults with hospital-acquired, ventilator-associated, and healthcare-associated pneumonia. Am J Respir Crit Care Med 2005; 171:388–416. - PubMed
1. Guyatt GH, Oxman AD, Vist GE et al. . GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 2008; 336:924–6. - PMC - PubMed
1. US Food and Drug Administration (FDA). Information for healthcare professionals: colistimethate (marketed as Coly-Mycin M and generic products). Available at: http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPa.... Accessed September 2014.
1. Garonzik SM, Li J, Thamlikitkul V et al. . Population pharmacokinetics of colistin methanesulfonate and formed colistin in critically ill patients from a multicenter study provide dosing suggestions for various categories of patients. Antimicrob Agents Chemother 2011; 55:3284–94. - PMC - PubMed
1. Nation RL, Li J, Cars O et al. . Framework for optimisation of the clinical use of colistin and polymyxin B: the Prato polymyxin consensus. Lancet Infect Dis 2015; 15:225–34. - PubMed

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Executive Summary: Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society

Affiliations

Executive Summary: Management of Adults With Hospital-acquired and Ventilator-associated Pneumonia: 2016 Clinical Practice Guidelines by the Infectious Diseases Society of America and the American Thoracic Society

Authors

Affiliations

Erratum in

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References

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