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Comment
. 2016 Aug 15;194(4):390-3.
doi: 10.1164/rccm.201603-0624ED.

Endothelial Glycocalyx: Not Just a Sugar Coat

Li Li  1 , Joseph V Bonventre  1   2
Affiliations
Comment

Endothelial Glycocalyx: Not Just a Sugar Coat

Li Li et al. Am J Respir Crit Care Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
Endothelial injury and glycocalyx disruption in acute kidney injury. (A) Normal and (B) injured glomerular endothelium. With injury, disruption of the glycocalyx can result in increased leukocyte– and platelet–endothelial interactions that can cause impaired capillary flow or obstruction. (C) Normal tubular epithelium and peritubular capillary endothelium separated by a small interstitial compartment. A glycocalyx coats the endothelium. (D) Disruption of the glycocalyx in peritubular capillaries may lead to increased leukocyte– and platelet–endothelial interactions, inflammation, interstitial edema, and reduced tubule oxygen supply, particularly in the outer medulla of the kidney. ECM = extracellular matrix; GAG = glycosaminoglycan; GBM = glomerular basement membrane; MØ = macrophage.
See this image and copyright information in PMC

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