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Comment
. 2016 Aug 15;6(8):e224.
doi: 10.1038/nutd.2016.31.

What are we to think when results from mouse research contradict those from human experiments and clinical practice?

Affiliations
Comment

What are we to think when results from mouse research contradict those from human experiments and clinical practice?

G Schofield et al. Nutr Diabetes. .
No abstract available

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References

    1. Lamont BJ, Waters MF, Andrikopoulos S. A low-carbohydrate high-fat diet increases weight gain and does not improve glucose tolerance, insulin secretion or β-cell mass in NZO mice. Nutr Diabetes 2016; 15: e194. - PMC - PubMed
    1. Pan HJ, Agate DS, King BL, Wu MK, Roderick SL, Leiter EH et al. A polymorphism in New Zealand inbred mouse strains that inactivates phosphatidylcholine transfer protein. FEBS Lett 2006; 580: 5953–5958. - PMC - PubMed
    1. Kluth O, Mirhashemi F, Scherneck S, Kaiser D, Kluge R, Neschen S et al. Dissociation of lipotoxicity and glucotoxicity in a mouse model of obesity associated diabetes: role of forkhead box O1 (FOXO1) in glucose-induced beta cell failure. Diabetologia 2011; 54: 605–616. - PMC - PubMed
    1. Sattar N, Gill JMR. Type 2 diabetes as a disease of ectopic fat? BMC Medicine 2014; 12: 123. - PMC - PubMed
    1. Haufe S, Engeli S, Kast P, Böhnke J, Utz W, Haas V et al. Randomized comparison of reduced fat and reduced carbohydrate hypocaloric diets on intrahepatic fat in overweight and obese human subjects. Hepatology 2011; 53: 1504–1514. - PubMed