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Review
. 2016 Sep;1380(1):230-234.
doi: 10.1111/nyas.13196. Epub 2016 Aug 15.

Epidemiology and mechanisms of gastroesophageal reflux disease in the elderly: a perspective

Mohammad Bashashati  1 , Irene Sarosiek  1 , Richard W McCallum  2
Affiliations
Review

Epidemiology and mechanisms of gastroesophageal reflux disease in the elderly: a perspective

Mohammad Bashashati et al. Ann N Y Acad Sci. 2016 Sep.

Abstract

Gastroesophageal reflux disease (GERD) seems to be more common in older individuals. Disturbed esophageal motility; anatomical disorders, such as hiatal hernia, increased obesity, defective mucosal integrity, and alteration in salivary secretion; and concomitant medications all attribute to the higher rate of GERD in the elderly. In this review, we discuss the underlying mechanisms that could explain this higher rate of GERD in the elderly.

Keywords: elderly; epidemiology; gastroesophageal reflux disease; pathophysiology; severity.

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