Reply to S. Zhang, L. Fornaro et al, and H.J. Lee et al
- PMID: 27528726
- PMCID: PMC5477929
- DOI: 10.1200/JCO.2016.69.1071
Reply to S. Zhang, L. Fornaro et al, and H.J. Lee et al
Comment on
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Randomized, Double-Blind, Placebo-Controlled Phase III Trial of Apatinib in Patients With Chemotherapy-Refractory Advanced or Metastatic Adenocarcinoma of the Stomach or Gastroesophageal Junction.J Clin Oncol. 2016 May 1;34(13):1448-54. doi: 10.1200/JCO.2015.63.5995. Epub 2016 Feb 16. J Clin Oncol. 2016. PMID: 26884585 Clinical Trial.
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Problematic Analysis and Inadequate Toxicity Data in Phase III Apatinib Trial in Gastric Cancer.J Clin Oncol. 2016 Nov 1;34(31):3821. doi: 10.1200/JCO.2016.67.3889. J Clin Oncol. 2016. PMID: 27528723 Free PMC article. No abstract available.
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Is Treatment-Emergent Toxicity a Biomarker of Efficacy of Apatinib in Gastric Cancer?J Clin Oncol. 2016 Nov 1;34(31):3823. doi: 10.1200/JCO.2016.68.8663. J Clin Oncol. 2016. PMID: 27528729 Free PMC article. No abstract available.
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Apatinib in Advanced Gastric Cancer: A Doubtful Step Forward.J Clin Oncol. 2016 Nov 1;34(31):3822-3823. doi: 10.1200/JCO.2016.68.6931. J Clin Oncol. 2016. PMID: 27528730 Free PMC article. No abstract available.
References
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- Li J, Qin S, Xu J, et al. Randomized, double-blind, placebo-controlled phase III trial of apatinib in patients with chemotherapy-refractory advanced or metastatic adenocarcinoma of the stomach or gastroesophageal junction. J Clin Oncol. 2016;34:1448–1454. - PubMed
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- US Food and Drug Administration Guidance for industry: E9 statistical principles for clinical trials. http://purl.access.gpo.gov/GPO/LPS117508.
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