Apatinib in Advanced Gastric Cancer: A Doubtful Step Forward
- PMID: 27528730
- PMCID: PMC5477932
- DOI: 10.1200/JCO.2016.68.6931
Apatinib in Advanced Gastric Cancer: A Doubtful Step Forward
Comment in
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Reply to S. Zhang, L. Fornaro et al, and H.J. Lee et al.J Clin Oncol. 2016 Nov 1;34(31):3823-3824. doi: 10.1200/JCO.2016.69.1071. J Clin Oncol. 2016. PMID: 27528726 Free PMC article. No abstract available.
Comment on
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Randomized, Double-Blind, Placebo-Controlled Phase III Trial of Apatinib in Patients With Chemotherapy-Refractory Advanced or Metastatic Adenocarcinoma of the Stomach or Gastroesophageal Junction.J Clin Oncol. 2016 May 1;34(13):1448-54. doi: 10.1200/JCO.2015.63.5995. Epub 2016 Feb 16. J Clin Oncol. 2016. PMID: 26884585 Clinical Trial.
References
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- Wilke H, Muro K, Van Cutsem E, et al. Ramucirumab plus paclitaxel versus placebo plus paclitaxel in patients with previously treated advanced gastric or gastro-oesophageal junction adenocarcinoma (RAINBOW): A double-blind, randomised phase 3 trial. Lancet Oncol. 2014;15:1224–1235. - PubMed
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- Chau I, Norman AR, Cunningham D, et al. Multivariate prognostic factor analysis in locally advanced and metastatic esophago-gastric cancer–pooled analysis from three multicenter, randomized, controlled trials using individual patient data. J Clin Oncol. 2004;22:2395–2403. - PubMed
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