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Case Reports
. 2016 Aug 16:2016:bcr2016217189.
doi: 10.1136/bcr-2016-217189.

Novel PPP1CB-ALK fusion protein in a high-grade glioma of infancy

Yasmin Aghajan  1 , Michael L Levy  2 , Denise M Malicki  3 , John Ross Crawford  4
Affiliations
Case Reports

Novel PPP1CB-ALK fusion protein in a high-grade glioma of infancy

Yasmin Aghajan et al. BMJ Case Rep. .
No abstract available

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Figures

Figure 1
Figure 1
Axial CT image at presentation showing large hyperdense lesion in right cerebral hemisphere with areas of acute haemorrhage, vasogenic oedema and midline shift.
Figure 2
Figure 2
Neuropathology reveals a hypercellular glial tumour with pleomorphic nuclei and endothelial proliferation consistent with a high-grade glioma (×400).
See this image and copyright information in PMC

References

    1. Chiarle R, Voena C, Ambrogio C et al. . The anaplastic lymphoma kinase in the pathogenesis of cancer. Nat Rev Cancer 2008;8:11–23. doi:10.1038/nrc2291 - DOI - PubMed
    1. Cho YL, Min JK, Roh KM et al. . Phosphoprotein phosphatase 1CB (PPP1CB), a novel adipogenic activator, promotes 3T3-L1 adipogenesis. Biochem Biophys Res Commun 2015;467:211–17. doi:10.1016/j.bbrc.2015.10.004 - DOI - PubMed

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