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. 2016 Sep;53(5):607-13.
doi: 10.1597/15-130.

Resolution of Otitis Media With Effusion in Children With Cleft Palate Followed Through Five Years of Age

Cuneyt M Alper, Joseph E Losee, James T Seroky, Ellen M Mandel, Beverly C Richert, William J Doyle

Resolution of Otitis Media With Effusion in Children With Cleft Palate Followed Through Five Years of Age

Cuneyt M Alper et al. Cleft Palate Craniofac J. 2016 Sep.

Abstract

Objective: To describe the temporal pattern of otitis media with effusion (OME) resolution for a cohort of nonsyndromic cleft palate children enrolled before palatoplasty and followed through 5 years of age.

Design: This is a prospective, longitudinal study of the time course for OME resolution in infants and children with palatal clefts.

Setting: Cleft Palate Craniofacial Center of a tertiary care pediatric hospital.

Participants: This study included 52 children with cleft palate (29 boys, 45 white, Veau 1 through 4) who had a Furlow-type palatoplasty between 10 and 24 months of age performed by one of six surgeons.

Interventions: Standard cleft palate management was supplemented with study visits to the research clinic pre- and postpalatoplasty and then yearly to 6 years of age for assessments of middle ear status by interval history, otoscopy, and tympanometry.

Main outcome measure: The main outcome measure was age at otitis media resolution defined as the age in years at the first in a sequence of "disease-free" diagnoses not interrupted or followed by any other diagnosis.

Results: The cumulative percent OME resolution for ears/children at ages <1, 1, 2, 3, 4, 5 years was 4.1/4.4, 14.3/10.9, 31.6/21.7, 45.9/37.0, 56.1/50.0, and 70.4/60.9%. OME resolution followed a simple linear time curve with slopes of 13.5% (confidence interval [CI] = 12.2% to 14.8%, r(2) = .99) and 11.9% (CI = 10.1% to 13.6%, r(2) = .99) resolutions per year for ears and children, respectively.

Conclusions: There is a natural, age-related pattern of resolution for persistent OME that affects most infants and young children with cleft palate that is not affected by palatoplasty.

Keywords: cleft palate; disease resolution; otitis media with effusion; prospective study.

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Figures

Figure 1
Figure 1
Cumulative frequency of ears (open circles) and children (closed squares) as a function of the age at OME resolution.
See this image and copyright information in PMC

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