Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Jul 29:10:1453-9.
doi: 10.2147/OPTH.S112166. eCollection 2016.

A review of the role of ultrasound biomicroscopy in glaucoma associated with rare diseases of the anterior segment

Giuseppe Mannino  1 , Barmak Abdolrahimzadeh  2 , Silvia Calafiore  1 , Gianmario Anselmi  1 , Cristina Mannino  1 , Alessandro Lambiase  3
Affiliations
Review

A review of the role of ultrasound biomicroscopy in glaucoma associated with rare diseases of the anterior segment

Giuseppe Mannino et al. Clin Ophthalmol. .

Abstract

Ultrasound biomicroscopy is a non-invasive imaging technique, which allows high-resolution evaluation of the anatomical features of the anterior segment of the eye regardless of optical media transparency. This technique provides diagnostically significant information in vivo for the cornea, anterior chamber, chamber angle, iris, posterior chamber, zonules, ciliary body, and lens, and is of great value in assessment of the mechanisms of glaucoma onset. The purpose of this paper is to review the use of ultrasound biomicroscopy in the diagnosis and management of rare diseases of the anterior segment such as mesodermal dysgenesis of the neural crest, iridocorneal endothelial syndrome, phakomatoses, and metabolic disorders.

Keywords: glaucoma; iridocorneal syndrome; metabolic disorders; neural crest; phakomatoses; rare diseases; ultrasound biomicroscopy.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Ultrasound biomicroscopy image using the Humphrey-Zeiss model 840, (San Leandro, CA, USA [50 MHz]) showing a case of Axenfeld–Rieger anomaly. Notes: The anterior chamber structures present keratoirido-lenticular contacts. Anterior synechiae are clearly revealed (arrow heads). The ciliary body appears adherent to the posterior iris surface (arrow).
Figure 2
Figure 2
Ultrasound biomicroscopy image using the Humphrey-Zeiss model 840 (San Leandro, CA, USA [50 MHz]) showing a case of sclerocornea with corneal thickening, irregular morphology, and internal hyper-reflectivity. Notes: The anterior chamber appears shallow. Reproduced with permission from Mannino G, Papale A, De Bella F. Biomicroscopia ad ultrasuoni [Ultrasound biomicroscopy]. Fabiano Editore; 2004.
Figure 3
Figure 3
Ultrasound biomicroscopy image using the Humphrey-Zeiss model 840 (San Leandro, CA, USA [50 MHz]) showing an eye with aniridia. Notes: The presence of an incomplete iris is shown with arrows. Reproduced with permission from Mannino G, Papale A, De Bella F. Biomicroscopia ad ultrasuoni [Ultrasound biomicroscopy]. Fabiano Editore; 2004.
Figure 4
Figure 4
Ultrasound biomicroscopy image using the Humphrey-Zeiss model 840 (San Leandro, CA, USA [50 MHz]) showing essential iris atrophy. Note: The iris is thinner than normal (arrows).
See this image and copyright information in PMC

References

    1. Pavlin CJ, Foster FS. Ultrasound biomicroscopy of the eye. New York: Springer & Verlag; 1995.
    1. Mannino G, Papale A, De Bella F. Biomicroscopia ad ultrasuoni [Ultrasound biomicroscopy] Fabiano Editore; 2004. Italian.
    1. Pavlin CJ, Haraseiwicz K, Sherar MD, Foster FS. Clinical use of ultrasound biomicroscopy. Ophthalmology. 1991;98(3):287–295. - PubMed
    1. Ishikawa H, Schuman JS. Anterior segment imaging: ultrasound biomicroscopy. Ophthalmol Clin North Am. 2004;17(1):7–20. - PMC - PubMed
    1. Kiryu J, Park M, Kobayashi H, Kondo T. Ultrasound biomicroscopy of the anterior segment of newborn infants. J Pediatr Ophthalmol Strabismus. 1998;35:320–322. - PubMed

LinkOut - more resources