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. 2016 Sep 27;115(7):876-86.
doi: 10.1038/bjc.2016.246. Epub 2016 Aug 18.

Is cancer survival associated with cancer symptom awareness and barriers to seeking medical help in England? An ecological study

Maja Niksic  1 , Bernard Rachet  2 , Stephen W Duffy  3 , Manuela Quaresma  2 , Henrik Møller  1 , Lindsay Jl Forbes  1
Affiliations

Is cancer survival associated with cancer symptom awareness and barriers to seeking medical help in England? An ecological study

Maja Niksic et al. Br J Cancer. .

Abstract

Background: Campaigns aimed at raising cancer awareness and encouraging early presentation have been implemented in England. However, little is known about whether people with low cancer awareness and increased barriers to seeking medical help have worse cancer survival, and whether there is a geographical variation in cancer awareness and barriers in England.

Methods: From population-based surveys (n=35 308), using the Cancer Research UK Cancer Awareness Measure, we calculated the age- and sex-standardised symptom awareness and barriers scores for 52 primary care trusts (PCTs). These measures were evaluated in relation to the sex-, age-, and type of cancer-standardised cancer survival index of the corresponding PCT, from the National Cancer Registry, using linear regression. Breast, lung, and bowel cancer survival were analysed separately.

Results: Cancer symptom awareness and barriers scores varied greatly between geographical regions in England, with the worst scores observed in socioeconomically deprived parts of East London. Low cancer awareness score was associated with poor cancer survival at PCT level (estimated slope=1.56, 95% CI: 0.56; 2.57). The barriers score was not associated with overall cancer survival, but it was associated with breast cancer survival (estimated slope=-0.66, 95% CI: -1.20; -0.11). Specific barriers, such as embarrassment and difficulties in arranging transport to the doctor's surgery, were associated with worse breast cancer survival.

Conclusions: Cancer symptom awareness and cancer survival are associated. Campaigns should focus on improving awareness about cancer symptoms, especially in socioeconomically deprived areas. Efforts should be made to alleviate barriers to seeking medical help in women with symptoms of breast cancer.

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Figures

Figure 1
Figure 1
Cancer symptom awareness score by PCT in England.
Figure 2
Figure 2
Barriers to help-seeking score by PCT in England.
Figure 3
Figure 3
The position of 52 PCTs with regard (direction: from left to right) to the cancer survival index, breast, lung, and bowel cancer survival (y axis), the cancer awareness score, and the cancer-specific symptom: an unexplained lump/swelling, persistent cough/hoarseness, and a change in bowel/bladder habits in each PCT (x axis), standardised by age and sex, and weighted for the inverse variance of appropriate survival estimates.
Figure 4
Figure 4
The position of 52 PCTs with regard (direction: from left to right) to the cancer survival index, breast, lung, and bowel cancer survival (y axis), standardised by age and sex, and weighted for the inverse variance of appropriate survival estimates.
See this image and copyright information in PMC

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