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Practice Guideline
. 2016 Aug;22 Suppl(Suppl 2):S25-57.
doi: 10.4103/1319-3767.188067.

SASLT guidelines: Update in treatment of Hepatitis C virus infection

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Practice Guideline

SASLT guidelines: Update in treatment of Hepatitis C virus infection

Abdullah S Alghamdi et al. Saudi J Gastroenterol. 2016 Aug.
No abstract available

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Figures

Figure 1
Figure 1
HCV genome organization. The HCV Open Reading Frame encodes three structural proteins, a small protein p7 ion channel, and 6 non-structural (NS) proteins. The structural proteins consist of core (c) proteins and envelop E proteins. The nonstructural proteins consist of NS2, NS3, NS4A, NS4B, NS5A, and NS5B types. Together, NS3/4A, NS4B, NS5A, and NS5B constitute the viral proteins of the replication machinery, which replicates the positive sense RNA genome through a negative strand intermediate. The viral RNA-dependent RNA polymerase NS5B is the key enzyme of RNA synthesis

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References

    1. Abdo AA, Sanai FM, Al-Faleh FZ. Epidemiology of viral hepatitis in Saudi Arabia: Are we off the hook? Saudi J Gastroenterol. 2012;18:349–57. - PMC - PubMed
    1. Alswaidi FM, O’Brien SJ. Is there a need to include HIV, HBV and HCV viruses in the Saudi premarital screening program on the basis of their prevalence and transmission risk factors? J Epidemiol Community Health. 2010;64:989–97. - PubMed
    1. Al Traif I, Al Balwi MA, Abdulkarim I, Handoo FA, Alqhamdi HS, Alotaibi M, et al. HCV genotypes among 1013 Saudi nationals: A multicenter study. Ann Saudi Med. 2013;33:10–2. - PMC - PubMed
    1. Al Ashgar HI, Khan MQ, Al-Ahdal M, Al Thawadi S, Helmy AS, Al Qahtani A, et al. Hepatitis C genotype 4: Genotypic diversity, epidemiological profile, and clinical relevance of subtypes in Saudi Arabia. Saudi J Gastroenterol. 2013;19:28–33. - PMC - PubMed
    1. Sanai FM, Helmy A, Dale C, Al-Ashgar H, Abdo AA, Katada K, et al. Updated thresholds for alanine aminotransferase do not exclude significant histological disease in chronic hepatitis C. Liver Int. 2011;31:1039–46. - PubMed

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