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Review
. 2016 Nov;30(11):1765-1774.
doi: 10.1002/ptr.5694. Epub 2016 Aug 19.

Overview of Oroxylin A: A Promising Flavonoid Compound

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Review

Overview of Oroxylin A: A Promising Flavonoid Compound

Lu Lu et al. Phytother Res. 2016 Nov.

Abstract

Oroxylin A is one of the main active components extracted from Scutellariae radix. It has been proved that oroxylin A possesses a broad spectrum of pharmacological functions, including anti-cancer, antiinflammation, neuroprotective, anti-coagulation and so on. The pharmacological activity of oroxylin A has been studied in vitro and on animal models, which reflected its promising potency in disease treatment. This review aims to recapitulate the pharmacological function and the molecular mechanisms of oroxylin A, as well as its sources, extraction, synthesis and toxicity study. These data confirmed the therapeutic potential of oroxylin A and provided reference for further development. Copyright © 2016 John Wiley & Sons, Ltd.

Keywords: anti-cancer; oroxylin A; pharmacological activity; review.

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