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Review
. 2016 Aug;32(3):273-80.
doi: 10.1016/j.soncn.2016.05.007. Epub 2016 Jul 29.

Cancer Prevention: HPV Vaccination

Tami L Thomas
Review

Cancer Prevention: HPV Vaccination

Tami L Thomas. Semin Oncol Nurs. 2016 Aug.

Abstract

Objectives: To provide an overview of human papillomavirus (HPV) vaccination as cancer prevention with current strategies that nurses can use to help patients and parents overcome barriers to HPV vaccination.

Data sources: Peer-reviewed literature, presentation abstracts, and current immunization recommendations from the Advisory Council on Immunization Practice.

Conclusion: Nurses can help prevent cancer by encouraging HPV vaccination during routine immunization and make HPV vaccination normal and routine.

Implications for nursing practice: A vaccine to reduce/eliminate HPV-related cancers enables nurses' at all educational levels to advocate for cancer prevention through initiation and completion of the HPV vaccine series.

Keywords: HPV vaccination; cancer; human papillomavirus; nursing practice; oncology nursing; prevention.

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Figures

Figure 1
Figure 1. Noninfectious HPV VLP (vaccine) versus Infectious HPV Virus
Credited to Dr. Timothy Baker with permission. Timothy S. Baker, Professor Departments of Chemistry & Biochemistry and Molecular Biology University of California, San Diego HPV – Human Papillomavirus HPV VLP – HPV Virus Like Particles – resembles HPV but is non-infectious Viral DNA – deoxyribonucleic acid: a main component of chromosomes and the material that transfers genetic characteristics, in this case the DNA of HPV L2, L2 protein – protein expressed by HPV subtypes 16 and 18 that are linked to cancer cell production Capsid Proteins - outer cap layer of the HPV also known as viral structural proteins which can result in the self-assembly of VPLs or Virus Like Particles
Figure 2
Figure 2
Suggested progressive steps to overcoming barriers to HPV vaccination series completion
See this image and copyright information in PMC

References

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    1. Kroger AT, Atkinson WL, Marcuse EK, Pickering LK. General recommendations on immunization: recommendations of the Advisory Committee on Immunization Practices (ACIP) MMWR Recomm Rep. 2006;55(RR-15):1–48. - PubMed

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