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Observational Study
. 2016 Oct;51(4):502-6.
doi: 10.1016/j.amepre.2016.07.003. Epub 2016 Aug 15.

Ideal Cardiovascular Health and Incident Cardiovascular Events: The Jackson Heart Study

Mark J Ommerborn  1 , Chad T Blackshear  2 , DeMarc A Hickson  3 , Michael E Griswold  2 , Japneet Kwatra  1 , Luc Djoussé  4 , Cheryl R Clark  5
Affiliations
Observational Study

Ideal Cardiovascular Health and Incident Cardiovascular Events: The Jackson Heart Study

Mark J Ommerborn et al. Am J Prev Med. 2016 Oct.

Abstract

Introduction: The epidemiology of American Heart Association ideal cardiovascular health (CVH) metrics has not been fully examined in African Americans. This study examines the associations of CVH metrics with incident cardiovascular disease (CVD) in the Jackson Heart Study, a longitudinal cohort study of CVD in African Americans.

Methods: Jackson Heart Study participants without CVD (n=4,702) were followed prospectively between 2000 and 2011. Incidence rates and Cox proportional hazard ratios estimated risks for incident CVD (myocardial infarction, stroke, cardiac procedures, and CVD mortality) associated with seven CVH metrics by sex. Analyses were performed in 2015.

Results: Participants were followed for a median of 8.3 years; none had ideal health on all seven CVH metrics. The prevalence of ideal health was low for nutrition, physical activity, BMI, and blood pressure metrics. The age-adjusted CVD incidence rate (IR) per 1,000 person years was highest for individuals with the least ideal health metrics: zero to one (IR=12.5, 95% CI=9.7, 16.1), two (IR=8.2, 95% CI=6.5, 10.4), three (IR=5.7, 95% CI=4.2, 7.6), and four or more (IR=3.4, 95% CI=2.0, 5.9). Adjusting for covariates, individuals with four or more ideal CVH metrics had lower risks of incident CVD compared with those with zero or one ideal CVH metric (hazard ratio, 0.29; 95% CI=0.17, 0.52; p<0.001).

Conclusions: African Americans with more ideal CVH metrics have lower risks of incident CVD. Comprehensive preventive behavioral and clinical supports should be intensified to improve CVD risk for African Americans with few ideal CVH metrics.

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Figures

Figure 1
Figure 1
Incidence rates for cardiovascular disease events by number of ideal cardiovascular health metrics by sex, the Jackson Heart Study. Notes: Cardiovascular disease incidence rates calculated via PROC GENMOD in SAS. The incidence rates are calculated per 1,000 person-years. CVH, cardiovascular health
See this image and copyright information in PMC

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