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. 2014 Oct;10(10):647-86.

Hepatitis D Virus: A Call to Screening

Joseph Ahn  1 , Robert G Gish  1
Affiliations

Hepatitis D Virus: A Call to Screening

Joseph Ahn et al. Gastroenterol Hepatol (N Y). 2014 Oct.

Abstract

Hepatitis D virus causes an aggressive viral hepatitis with a virulent course of progression to cirrhosis and hepatic decompensation. It relies on hepatitis B coinfection for its pathogenesis and propagation. Hepatitis D virus had become the forgotten virus, with reduced public awareness, medical interest, and research support. Recently, there has been a resurgence of awareness and interest in hepatitis D, with improvements in diagnostic testing and establishment of international collaborative efforts to improve therapy. This article provides a framework to understand the impetus for increased screening as well as to identify key issues toward which collaborative efforts can be directed.

Keywords: Hepatitis delta; cirrhosis; interferon; pegylated interferon; prenylation inhibitors.

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