Comment
doi: 10.1016/j.molcel.2016.08.003.
IRE1 Sulfenylation by Reactive Oxygen Species Coordinates Cellular Stress Signaling
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- PMID: 27540852
- DOI: 10.1016/j.molcel.2016.08.003
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IRE1 Sulfenylation by Reactive Oxygen Species Coordinates Cellular Stress Signaling
Mol Cell.
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Free article
Abstract
In this issue of Molecular Cell, Hourihan et al. (2016) show that sulfenylation of IRE1 by reactive oxygen species inhibits the role of IRE1 in the Unfolded Protein Response and activates a SKN-1/Nrf2-dependent response to oxidative stress.
Copyright © 2016 Elsevier Inc. All rights reserved.
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