Asymptomatic severe aortic stenosis with normal left ventricular function - A review
- PMID: 27543485
- PMCID: PMC4990807
- DOI: 10.1016/j.ihj.2016.05.006
Asymptomatic severe aortic stenosis with normal left ventricular function - A review
Abstract
Aortic stenosis (AS) is one of the commonest forms of acquired valvular heart disease. Aortic valve replacement (AVR) is the treatment of choice for symptomatic severe AS. Conservative management is usually advocated for asymptomatic severe AS. But there are data on predictors to identify subsets of asymptomatic AS patients at high risk of cardiac events in whom early surgical intervention is warranted. Non-invasive tests like exercise stress test, exercise echocardiography will help us to identify those who are at high risk of developing early symptoms due to LV dysfunction and also those at high risk of sudden death. In this article, an attempt is made to review the literature on this subset of asymptomatic severe AS to help clinicians to decide regarding the need for early aortic valve replacement in them.
Keywords: Aortic stenosis with normal LV function; Aortic valve replacement surgery; Asymptomatic aortic stenosis.
Copyright © 2016 Cardiological Society of India. Published by Elsevier B.V. All rights reserved.
Figures
Similar articles
-
Incremental Prognostic Use of Left Ventricular Global Longitudinal Strain in Asymptomatic/Minimally Symptomatic Patients With Severe Bioprosthetic Aortic Stenosis Undergoing Redo Aortic Valve Replacement.Circ Cardiovasc Imaging. 2017 Jun;10(6):e005942. doi: 10.1161/CIRCIMAGING.116.005942. Circ Cardiovasc Imaging. 2017. PMID: 28559420
-
Rationale and design of the randomized, controlled Early Valve Replacement Guided by Biomarkers of Left Ventricular Decompensation in Asymptomatic Patients with Severe Aortic Stenosis (EVOLVED) trial.Am Heart J. 2019 Jun;212:91-100. doi: 10.1016/j.ahj.2019.02.018. Epub 2019 Mar 15. Am Heart J. 2019. PMID: 30978556 Clinical Trial.
-
Value of exercise testing to evaluate the indication for surgery in asymptomatic patients with valvular aortic stenosis.J Heart Valve Dis. 2002 Mar;11(2):204-9. J Heart Valve Dis. 2002. PMID: 12000161
-
Optimal Threshold of Left Ventricular Ejection Fraction for Aortic Valve Replacement in Asymptomatic Severe Aortic Stenosis: A Systematic Review and Meta-Analysis.J Am Heart Assoc. 2021 Apr 6;10(7):e020252. doi: 10.1161/JAHA.120.020252. Epub 2021 Mar 31. J Am Heart Assoc. 2021. PMID: 33787311 Free PMC article.
-
Systematic review and meta-analysis of early aortic valve replacement versus conservative therapy in patients with asymptomatic aortic valve stenosis with preserved left ventricle systolic function.Open Heart. 2024 Jan 8;11(1):e002511. doi: 10.1136/openhrt-2023-002511. Open Heart. 2024. PMID: 38191233 Free PMC article.
Cited by
-
Electrocardiographic appearance of aortic stenosis before and after aortic valve replacement.Ann Noninvasive Electrocardiol. 2017 Sep;22(5):e12457. doi: 10.1111/anec.12457. Epub 2017 Apr 21. Ann Noninvasive Electrocardiol. 2017. PMID: 28429500 Free PMC article.
-
Serum copeptin might improve risk stratification and management of aortic valve stenosis: a review of pathophysiological insights and practical implications.Ther Adv Cardiovasc Dis. 2019 Jan-Dec;13:1753944719826420. doi: 10.1177/1753944719826420. Ther Adv Cardiovasc Dis. 2019. PMID: 30803406 Free PMC article. Review.
References
-
- Ross J., Braunwald E. Aortic stenosis. Circulation. 1968;36:381–386. - PubMed
-
- Schwartz F., Baumann P., Manthey J. The effect of aortic valve replacement on survival. Circulation. 1982;66:1105–1110. - PubMed
-
- Bonow R.O., Carabello B.A., Chatterjee K. ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing Committee to Revise the 1998 guidelines for the management of patient with valvular heart disease) developed in collaboration with the Society of Cardiovascular Anesthesiologists endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons. J Am Coll Cardiol. 2006;48:e1–e148. - PubMed
-
- Iung B., Baron G., Butchart E.G. A prospective survey of patients with valvular heart disease in Europe: the Euro Heart Survey on Valvular Heart Disease. Eur Heart J. 2003;24:1231–1243. - PubMed
-
- Cannegieter S.C., Rosendaal F.R., Briet E. Thromboembolic and bleeding complications in patients with mechanical heart valve prostheses. Circulation. 1994;89:635–641. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials