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Case Reports
. 1989 May;7(1):25-9.
doi: 10.1007/BF00149375.

Fibrous dysplasia of the skull with acromegaly and sarcomatous transformation. Two cases with a review of the literature

Affiliations
Case Reports

Fibrous dysplasia of the skull with acromegaly and sarcomatous transformation. Two cases with a review of the literature

A Mortensen et al. J Neurooncol. 1989 May.

Abstract

Two cases of fibrous dysplasia of the skull are reported. Both patients were young women with acromegaly and were treated with radiotherapy. Progressive pareses of cranial nerves, pain, and a malignant course of the disease were characteristic in both patients, and the diagnosis of osteogenous sarcoma proved in one of them by histological examination. The clinical picture of fibrous dysplasia of the skull and the role of radiotherapy with the risk of development of malignancy is discussed.

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