Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2017 Jun;10(6):711-713.
doi: 10.1016/j.jcmg.2016.06.004. Epub 2016 Aug 17.

Cardiac MRI Findings Suggest Myocarditis in Severe Ebola Virus Disease

Daniel S Chertow, Richard W Childs, Andrew E Arai, Richard T Davey Jr
Case Reports

Cardiac MRI Findings Suggest Myocarditis in Severe Ebola Virus Disease

Daniel S Chertow et al. JACC Cardiovasc Imaging. 2017 Jun.
No abstract available

PubMed Disclaimer

Figures

Figure 1.
Figure 1.. Cardiac MRI studies were performed following recovery from severe Ebola virus disease on clinical illness day 32 (study 1) and 11 weeks later (study 2).
Study 1 showed mildly reduced ejection fraction (LVEF 52%). Late gadolinium enhancement (LGE) was initially unremarkable (red arrow, study 1). There was evidence of mild edema or inflammation of the midwall of the basal inferolateral segment of the left ventricle with a focal abnormal spot on native T1 and ECV (orange and cyan arrows) but also milder abnormalities in surrounding myocardium excluding the spot (see table). Quantitative maps of myocardial T2 showed a non-significant elevation in mid-myocardial T2 in the interventricular septum. On study 2, the T1 and ECV abnormalities normalized except for a sub-gram region localized to the region of most severe abnormality seen on the initial study. Interval development of fibrosis was evident on LGE images (red arrow on study 2). LVEF remained mildly abnormal (51%).
See this image and copyright information in PMC

References

    1. Chertow DS, Nath A, Suffredini AF, Danner RL, Reich DS, Bishop RJ, Childs RW, Arai AE, Palmore TN, Lane HC, Fauci AS, Davey RT. Severe Meningoencephalitis in a Case of Ebola Virus Disease: A Case Report. Ann Intern Med 2016. - PMC - PubMed
    1. Pollack A, Kontorovich AR, Fuster V, Dec GW. Viral myocarditis--diagnosis, treatment options, and current controversies. Nat Rev Cardiol 2015; 12: 670–680. - PubMed
    1. Martines RB, Ng DL, Greer PW, Rollin PE, Zaki SR. Tissue and cellular tropism, pathology and pathogenesis of Ebola and Marburg viruses. J Pathol 2015; 235: 153–174. - PubMed
    1. Lazzerini PE, Capecchi PL, Laghi-Pasini F. Long QT Syndrome: An Emerging Role for Inflammation and Immunity. Front Cardiovasc Med 2015; 2: 26. - PMC - PubMed