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Case Reports
. 2016 Oct 5;95(4):793-794.
doi: 10.4269/ajtmh.15-0860. Epub 2016 Aug 22.

Successful Treatment of Cutaneous Leishmaniasis with Topical Paramomycin in a Child After Treatment Failure with Systemic Fluconazole

Anila Chacko  1 , Marissa Joseph  2 , Timothy Feltis  3 , Shaun K Morris  4
Affiliations
Case Reports

Successful Treatment of Cutaneous Leishmaniasis with Topical Paramomycin in a Child After Treatment Failure with Systemic Fluconazole

Anila Chacko et al. Am J Trop Med Hyg. .

Abstract

It is challenging to find safe, nonscarring and noninvasive treatment of facial cutaneous leishmaniasis (CL) in children. Herein, we report a child with CL from a region endemic for Leishmania tropica, whose lesion persisted after treatment with oral fluconazole but responded to topical paromomycin. Paromomycin should be considered early for treatment of Old World CL and is a well-tolerated and effective mode of therapy for facial lesions.

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Figures

Figure 1.
Figure 1.
Lesion at presentation and at follow-up 1 year later.
Figure 2.
Figure 2.
Section from skin showing numerous Leishmania organisms (red arrows) in dermis with surrounding inflammatory response (magnification ×400).
See this image and copyright information in PMC

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