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Review
. 2016 Nov;19(6):401-407.
doi: 10.1097/MCO.0000000000000316.

Mediterranean diet and life expectancy; beyond olive oil, fruits, and vegetables

Miguel A Martinez-Gonzalez  1 , Nerea Martin-Calvo
Affiliations
Review

Mediterranean diet and life expectancy; beyond olive oil, fruits, and vegetables

Miguel A Martinez-Gonzalez et al. Curr Opin Clin Nutr Metab Care. 2016 Nov.

Abstract

Purpose of review: The recent relevant evidence of the effects of the Mediterranean diet (MedDiet) and lifestyle on health (2015 and first months of 2016).

Recent findings: Large observational prospective epidemiological studies with adequate control of confounding and two large randomized trials support the benefits of the Mediterranean dietary pattern to increase life expectancy, reduce the risk of major chronic disease, and improve quality of life and well-being. Recently, 19 new studies from large prospective studies showed - with nearly perfect consistency - strong benefits of the MedDiet to reduce the risk of myocardial infarction, stroke, total mortality, heart failure, and disability. Interestingly, two large and well conducted cohorts reported significant cardiovascular benefits after using repeated measurements of diet during a long follow-up period. In addition, Prevención con Dieta Mediterránea, the largest randomized trial with MedDiet, recently reported benefits of this dietary pattern to prevent cognitive decline and breast cancer.

Summary: In the era of evidence-based medicine, the MedDiet represents the gold standard in preventive medicine, probably because of the harmonic combination of many elements with antioxidant and anti-inflammatory properties, which overwhelm any single nutrient or food item. The whole seems more important than the sum of its parts.

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Conflict of interest statement

Conflict of Interest: The authors have no conflict of interest.

References

    1. Lim SS, Vos T, Flaxman AD, Danaei G, et al. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010 a systematic analysis for the Global Burden of Disease Study 2010. Lancet. 2012;380:2224–60. - PMC - PubMed
    1. Hu FB. Dietary pattern analysis: a new direction in nutritional epidemiology. Curr Opin Lipidol. 2002;13:3–9. - PubMed
    1. Martinez-Gonzalez MA, Bes-Rastrollo M. Dietary patterns, Mediterranean diet, and cardiovascular disease. Curr Opin Lipidol. 2014;25:20–6. “This is a systematic review with quantitative meta-analysis to assess the effect of the Mediterranean dietary pattern to prevent cardiovascular disease. Two different meta-analyses are included, one for observational studies and another for randomized trials”. - PubMed
    1. Martínez-González MA, Salas-Salvadó J, Estruch R, et al. Benefits of the Mediterranean Diet: Insights from the PREDIMED Study. Prog Cardiovasc Dis. 2015;58:50–60. “In this study, both the Mediterranean Diet supplemented with extra virgin olive oil and the Mediterranean Diet supplemented with nuts showed significant improvements in classical and emerging cardiovascular risk factors”. - PubMed
    1. Trichopoulou A, Martínez-González MA, Tong TY, et al. Definitions and potential health benefits of the Mediterranean diet: views from experts around the world. BMC Med. 2014;12:112. - PMC - PubMed

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