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. 2017 Mar;18(3):141-150.
doi: 10.1111/hiv.12408. Epub 2016 Aug 24.

The HIV/AIDS epidemic among young people in China between 2005 and 2012: results of a spatial temporal analysis

X Zhang  1   2 , W Tang  3   4 , Y Li  5 , T Mahapatra  6 , Y Feng  1 , M Li  1 , F Chen  1 , P Li  1 , J Xing  7 , S Qian  8 , L Ge  1 , K Bu  1 , S Mahapatra  6 , S Tang  3   4 , L Wang  1 , N Wang  1
Affiliations

The HIV/AIDS epidemic among young people in China between 2005 and 2012: results of a spatial temporal analysis

X Zhang et al. HIV Med. 2017 Mar.

Abstract

Objectives: Despite a recent increase in the HIV/AIDS epidemic among young people in China, youth-specific HIV data are limited.

Methods: In total, 56 621 individuals with HIV/AIDS, aged 15-24 years, registered in the Case Reporting System of China between 2005 and 2012 and having complete spatial information were included in the present analysis. Spatial autocorrelation (general and local) and space-time scanning were performed using the ArcGIS 10.2 and SaTScan 9.3 software, respectively.

Results: During 2005-2012, the number of reported HIV/AIDS cases and the proportion of HIV cases increased while the proportion of AIDS cases decreased. Sexual contact became the predominant route of transmission in later years. Spatial analysis showed marked geographical variations in HIV infection among young people throughout China during 2005-2012. The number of new hotspots increased over time. They were mainly localized to southeastern coastal areas, southwestern frontier provinces or autonomous regions (of Guangxi, Yunnan and Sichuan) and Beijing municipality. Later these hotspots disappeared and new hotspots were found in the northeast of the country. Significant clusters of HIV-positive cases were identified in three different time periods, which indicated high HIV transmission among young Chinese people in the recent past. The risk of HIV infection was highest in the first cluster (2009-2012; this cluster was the largest in size) covering the provinces of Guizhou and Yunnan, the Chongqing municipality, Guangxi, and the province of Sichuan. The second cluster (2010-2012) was mostly located in Shanghai, South Jiangsu, Zhejiang and South Anhui, while the third cluster (2010-2012) was located in Beijing and Tianjin.

Conclusions: Target-specific comprehensive behavioural interventions are urgently needed to contain the HIV epidemic among young people.

Keywords: HIV; China; cluster; hotspots; spatial analysis; young people.

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Conflict of interest statement

Conflicts of interest: None

Figures

Figure 1
Figure 1
Geographical distribution of the total number of reported young HIV/AIDS cases at city level in the years 2005, 2008, 2010 and 2012
Figure 2
Figure 2
Hot spots of young HIV/AIDS cases at city level by year Space-time scanning
Figure 3
Figure 3
Case clusters among young people through space-time analysis, 2005–2012, China
See this image and copyright information in PMC

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References

    1. Tang W, Babu GR, Li J, et al. The difference between HIV and syphilis prevalence and incidence cases: results from a cohort study in Nanjing, China, 2008–2010. International journal of STD & AIDS. 2014 0956462414550170. - PMC - PubMed
    1. Binagwaho A, Fuller A, Kerry V, et al. Adolescents and the right to health: eliminating age-related barriers to HIV/AIDS services in Rwanda. AIDS Care. 2012;24(7):936–42. doi: 10.1080/09540121.2011.648159. [published Online First: Epub Date]|. - DOI - PubMed
    1. Pettifor A, Bekker LG, Hosek S, et al. Preventing HIV among young people: research priorities for the future. J Acquir Immune Defic Syndr. 2013;63(Suppl 2):S155–60. doi: 10.1097/QAI.0b013e31829871fb. [published Online First: Epub Date]|. - DOI - PMC - PubMed
    1. Francis B, Taboada F, Andiorio E, et al. Demonstration of Improved Sensitivity and Specificity in Blood-Donors by a Prototype Hcv-3. 0 Elisa. Transfusion. 1993;33(9):S32–S32.
    1. Riezuboj JI, Parker D, Civeira MP, et al. Detection of Hepatitis-C Virus-Antibodies with New Recombinant Antigens - Assessment in Chronic Liver-Diseases. Journal of Hepatology. 1992;15(3):309–13. - PubMed

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