Sleep: Switching Off the Off-Switch
- PMID: 27554656
- DOI: 10.1016/j.cub.2016.06.059
Sleep: Switching Off the Off-Switch
Abstract
What are the synaptic drives controlling the sleep-wake circuitry in the mammalian brain? In a new study it was found that GABAergic cells in posterior lateral hypothalamus inhibit sleep-promoting anterior hypothalamic cells to cause waking, whereas their inhibition augments sleep.
Copyright © 2016 Elsevier Ltd. All rights reserved.
Comment on
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A Novel Population of Wake-Promoting GABAergic Neurons in the Ventral Lateral Hypothalamus.Curr Biol. 2016 Aug 22;26(16):2137-43. doi: 10.1016/j.cub.2016.05.078. Epub 2016 Jul 14. Curr Biol. 2016. PMID: 27426511 Free PMC article.
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