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. 2015 Oct;5(5):345.
doi: 10.4172/2161-069X.1000345. Epub 2015 Oct 5.

Increased Incidence of Early Onset Colorectal Cancer in Arizona: A Comprehensive 15-year Analysis of the Arizona Cancer Registry

Hassan Aziz  1 , Viraj Pandit  1 , Ryan M DiGiovanni  1 , Eric Ohlson  1 , Angelika C Gruessner  2 , Jana Jandova  3 , Valentine N Nfonsam  1
Affiliations

Increased Incidence of Early Onset Colorectal Cancer in Arizona: A Comprehensive 15-year Analysis of the Arizona Cancer Registry

Hassan Aziz et al. J Gastrointest Dig Syst. 2015 Oct.

Abstract

Introduction: The aim of this study was to investigate and analyze the incidence of early-onset colorectal cancer in Arizona, using the Arizona Cancer Registry.

Methods: We performed a retrospective analysis of patients with colorectal cancer reported in the Arizona Cancer Registry from 1995-2010. Outcome measure: incidence of CRC in patients younger than 50 years.

Results: 39,623 cases of colorectal cancer were reported to the Arizona Cancer Registry during a period of 15 years. Overall, there was a 17% decrease in the incidence of CRC. However, there was a 23% increase in incidence among patients in the age group 10-50. During the same time period, 15% and 41% increase in the incidence of colon and rectal cancer was observed, respectively. The most significant increase (102%) in overall CRC incidence was seen in the age group 10-29. The highest increase (110%) in incidence of colon cancer was observed in the same age group, while the most significant increase in incidence rates (225%) of rectal cancer was seen in the age group 30-34.

Conclusion: Although there is an overall decrease in incidence of colorectal cancer in Arizona, alarming increase in incidence of early-onset CRC was observed; mirroring the national trends.

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Figures

Figure 1
Figure 1
Overall incidence of colorectal cancer in Arizona State between 1995 and 2010.
Figure 2
Figure 2
Incidence of colorectal cancer in Arizona among two age groups, <50 and >50.
Figure 3
Figure 3
Incidence of colorectal cancer in various age groups.
Figure 4
Figure 4
Incidence of colorectal cancer in a group of patients younger than 50 based on anatomic location of tumor.
Figure 5
Figure 5
Standard residuals for colorectal cancer stages.
See this image and copyright information in PMC

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