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. 2016 Jul-Aug;19(4):328-31.
doi: 10.4103/0972-0707.186449.

In vitro evaluation of remineralization efficacy of different calcium- and fluoride-based delivery systems on artificially demineralized enamel surface

Aparajita Gangrade  1 , Vandana Gade  1 , Sanjay Patil  1 , Jaykumar Gade  2 , Deepika Chandhok  1 , Deepa Thakur  1
Affiliations

In vitro evaluation of remineralization efficacy of different calcium- and fluoride-based delivery systems on artificially demineralized enamel surface

Aparajita Gangrade et al. J Conserv Dent. 2016 Jul-Aug.

Abstract

Background: Caries is the most common dental disease facing the world population. Caries can be prevented by remineralizing early enamel lesions.

Aim: To evaluate remineralization efficacy of stannous fluoride (SnF2), casein phosphopeptide-amorphous calcium phosphate with fluoride (CPP-ACPF) and calcium sucrose phosphate (CaSP).

Materials and methods: Fifty enamel samples were taken; they were divided into five groups (n = 10). Demineralization was carried out with Groups A, B, C, and E. Remineralization was carried out with Groups A, B, and C for 7 days using SnF2, CPP-ACPF, and CaSP, respectively. In Group D, no surface treatment was carried out, to mark as positive control whereas Group E was kept as negative control with only surface demineralization of enamel. Enamel microhardness was tested using Vickers's microhardness tester after 7 day remineralization regime.

Statistical analysis: One-way analysis of variance and post hoc Tukey tests were performed.

Results: The mean microhardness values in descending order: Positive control > SnF2> CaSP > CPP-ACPF > negative control.

Conclusion: All remineralizing agents showed improved surface remineralization. However, complete remineralization did not occur within 7 days. SnF2 showed the highest potential for remineralization followed by CaSP and CPP-ACPF.

Keywords: Calcium sucrose phosphate; caries prevention; casein phosphopeptide-amorphous calcium phosphate with fluoride; microhardness; remineralization; stannous fluoride.

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