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Comment
. 2016 Aug 25;166(5):1078-1079.
doi: 10.1016/j.cell.2016.08.011.

The Whole (Cell) Is Less Than the Sum of Its Parts

Jonathan G Van Vranken  1 , Jared Rutter  2
Affiliations
Comment

The Whole (Cell) Is Less Than the Sum of Its Parts

Jonathan G Van Vranken et al. Cell. .

Abstract

Despite advances in metabolite profiling, a full picture of the metabolic landscape of the cell has been limited by sub-cellular compartmentalization, which segregates distinct nutrient pools into membrane-bound organelles. Now, Chen et al. describe methods for overcoming this hurdle and provide a new quantitative picture of the mitochondrial metabolome.

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Figures

Figure 1
Figure 1. The Value of Spatial Resolution in Weather Forecasting
(A) A weather map describing the forecast of a number of cities across North America. (B) A low-resolution forecast of the United States of America (analogous to whole-cell metabolite profiling). (C) A high-resolution forecast of the United States of America (analogous to compartment-specific metabolite profiling).
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Comment on

References

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