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. 2016 Sep 16;18(18):4488-90.
doi: 10.1021/acs.orglett.6b02203. Epub 2016 Aug 29.

Total Synthesis of (+)-Vicenin-2

Thanh C Ho  1 , Haruki Kamimura  1 , Ken Ohmori  1 , Keisuke Suzuki  1
Affiliations

Total Synthesis of (+)-Vicenin-2

Thanh C Ho et al. Org Lett. .

Abstract

The bis-C-glucosyl flavonoid vicenin-2 (1) has been synthesized by exploiting bis-C-glycosylation of 1,3,5-trifluorobenzene and aromatic nucleophilic substitution to transform fluorine atoms to oxygen functions in excellent yield.

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