Review
doi: 10.1002/cbin.10672.
Epub 2016 Sep 20.
Chromatin fibers: from classical descriptions to modern interpretation
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- PMID: 27569720
- DOI: 10.1002/cbin.10672
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Review
Chromatin fibers: from classical descriptions to modern interpretation
Cell Biol Int.
2016 Nov.
Abstract
The first description of intrachromosomal fibers was made by Baranetzky in 1880. Since that time, a plethora of fibrillar substructures have been described inside the mitotic chromosomes, and published data indicate that chromosomes may be formed as a result of the hierarchical folding of chromatin fibers. In this review, we examine the evolution and the current state of research on the morphological organization of mitotic chromosomes.
Keywords: 30 nm fiber; chromomere; chromonema; chromosome; nucleosome.
© 2016 International Federation for Cell Biology.
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