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Review
. 2016 Aug 14;22(30):6906-16.
doi: 10.3748/wjg.v22.i30.6906.

Chinese expert consensus on cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal malignancies

Yan Li  1 , Yun-Feng Zhou  1 , Han Liang  1 , Hua-Qing Wang  1 , Ji-Hui Hao  1 , Zheng-Gang Zhu  1 , De-Seng Wan  1 , Lun-Xiu Qin  1 , Shu-Zhong Cui  1 , Jia-Fu Ji  1 , Hui-Mian Xu  1 , Shao-Zhong Wei  1 , Hong-Bin Xu  1 , Tao Suo  1 , Shu-Jun Yang  1 , Cong-Hua Xie  1 , Xiao-Jun Yang  1 , Guo-Liang Yang  1
Affiliations
Review

Chinese expert consensus on cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal malignancies

Yan Li et al. World J Gastroenterol. .

Abstract

Locoregional spread of abdominopelvic malignant tumors frequently results in peritoneal carcinomatosis (PC). The prognosis of PC patients treated by conventional systemic chemotherapy is poor, with a median survival of < 6 mo. However, over the past three decades, an integrated treatment strategy of cytoreductive surgery (CRS) + hyperthermic intraperitoneal chemotherapy (HIPEC) has been developed by the pioneering oncologists, with proved efficacy and safety in selected patients. Supported by several lines of clinical evidence from phases I, II and III clinical trials, CRS + HIPEC has been regarded as the standard treatment for selected patients with PC in many established cancer centers worldwide. In China, an expert consensus on CRS + HIPEC has been reached by the leading surgical and medical oncologists, under the framework of the China Anti-Cancer Association. This expert consensus has summarized the progress in PC clinical studies and systematically evaluated the CRS + HIPEC procedures in China as well as across the world, so as to lay the foundation for formulating PC treatment guidelines specific to the national conditions of China.

Keywords: Colorectal cancer; Cytoreductive surgery; Expert consensus; Gastric cancer; Intraperitoneal hyperthermic chemotherapy; Ovarian cancer; Peritoneal carcinomatosis; Peritoneal mesothelioma; Peritoneal sarcoma; Pseudomyxoma Peritonei.

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Figures

Figure 1
Figure 1
Clinical pathway for treatment of peritoneal carcinomatosis based on diagnostic systems. PCI: Peritoneal cancer index; CEA: Carcinoembryonic antigen; CA: Carbohydrate antigen; CT: Computed tomography; CRS: Cytoreductive surgery; HIPEC: Hyperthermic intraperitoneal chemotherapy.
Figure 2
Figure 2
Peritoneal carcinomatosis index staging system[31]. PCI: Peritoneal cancer index.
See this image and copyright information in PMC

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