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Review
. 2017 Jun;7(2):364-370.
doi: 10.1007/s13142-015-0346-8.

The measurement of patient attitudes regarding prenatal and preconception genetic carrier screening and translational behavioral medicine: an integrative review

Jennifer J Shiroff  1 , Mathew J Gregoski  2
Affiliations
Review

The measurement of patient attitudes regarding prenatal and preconception genetic carrier screening and translational behavioral medicine: an integrative review

Jennifer J Shiroff et al. Transl Behav Med. 2017 Jun.

Abstract

Measurement of recessive carrier screening attitudes related to conception and pregnancy is necessary to determine current acceptance, and whether behavioral intervention strategies are needed in clinical practice. To evaluate quantitative survey instruments to measure patient attitudes regarding genetic carrier testing prior to conception and pregnancy databases examining patient attitudes regarding genetic screening prior to conception and pregnancy from 2003-2013 were searched yielding 344 articles; eight studies with eight instruments met criteria for inclusion. Data abstraction on theoretical framework, subjects, instrument description, scoring, method of measurement, reliability, validity, feasibility, level of evidence, and outcomes was completed. Reliability information was provided in five studies with an internal consistency of Cronbach's α >0.70. Information pertaining to validity was presented in three studies and included construct validity via factor analysis. Despite limited psychometric information, these questionnaires are self-administered and can be briefly completed, making them a feasible method of evaluation.

Keywords: Attitude; Conception; Genetic testing; Integrative review; Patient; Pregnancy.

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Conflict of interest statement

Compliance with ethical standards:

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Conflict of interest

The authors declare that they have no competing interests.

Declaration of original work

The authors declare that the work described has not been published and is not under consideration for publication elsewhere.

Declaration of overlapping reports

The authors deny any previous reporting of this data.

No animal or human studies were carried out by the authors for this article.

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