Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Nov;26(11):2793-2801.
doi: 10.1007/s11695-016-2347-1.

Adipokine Pattern After Bariatric Surgery: Beyond the Weight Loss

Gian Franco Adami  1   2 , Nicola Scopinaro  3   4 , Renzo Cordera  3
Affiliations
Review

Adipokine Pattern After Bariatric Surgery: Beyond the Weight Loss

Gian Franco Adami et al. Obes Surg. 2016 Nov.

Abstract

Besides the role in energy storing and body health isolating, adipose tissue produces proteins, the so-called adipokines, with pro-inflammatory or anti-inflammatory actions that contribute to metabolic control and to appetite and energy expenditure regulation. The marked adipose tissue loss following bariatric surgery corresponds to a rearrangement of serum adipokine pattern, with increase of anti-inflammatory and decrease of pro-inflammatory agents. This might play a relevant role in the postoperative improvement of metabolic conditions. However, after surgically induced weight loss, other investigations failed to evidence significant modifications of serum concentration of some adipokines. This review speculates that the composition of adipose tissue lost could influence postoperative changes in some adipokine concentration and that an adequate adipokine pattern plays a pivotal role for the long-term metabolic outcome.

Keywords: Adipokines; Bariatric surgery; Obesity.

PubMed Disclaimer

References

    1. Diabetes Res Clin Pract. 2015 Mar;107(3):320-31 - PubMed
    1. Metabolism. 2015 Jan;64(1):131-45 - PubMed
    1. Mol Metab. 2014 Jan 21;3(3):230-40 - PubMed
    1. Br J Nutr. 2004 Sep;92 (3):347-55 - PubMed
    1. Best Pract Res Clin Endocrinol Metab. 2013 Apr;27(2):163-77 - PubMed

LinkOut - more resources