Genomic landscape of the Greater Middle East
- PMID: 27573686
- DOI: 10.1038/ng.3652
Genomic landscape of the Greater Middle East
Abstract
Study of the Greater Middle East (GME), home to approximately 10% of the world's population, has made invaluable contributions to the characterization of rare genetic disease, especially recessive conditions arising from the tradition of consanguinity and large families with multiple children. A new study now reports 1,111 unrelated exomes from the GME and provides a comprehensive view of genetic variation for enhanced discovery of disease-associated genes.
Comment on
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Characterization of Greater Middle Eastern genetic variation for enhanced disease gene discovery.Nat Genet. 2016 Sep;48(9):1071-6. doi: 10.1038/ng.3592. Epub 2016 Jul 18. Nat Genet. 2016. PMID: 27428751 Free PMC article.
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