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Review
. 2016:937:171-81.
doi: 10.1007/978-3-319-42059-2_9.

Circulating Non-coding RNA as Biomarkers in Colorectal Cancer

Manuela Ferracin  1 , Laura Lupini  2 , Alessandra Mangolini  2 , Massimo Negrini  2
Affiliations
Review

Circulating Non-coding RNA as Biomarkers in Colorectal Cancer

Manuela Ferracin et al. Adv Exp Med Biol. 2016.

Abstract

Recent studies suggested that colorectal cancer influences the types and quantity of nucleic acids - especially microRNAs - detected in the bloodstream. Concentration of circulating (cell-free) microRNAs, and possibly of other non-coding RNAs, could therefore serve as valuable colorectal cancer biomarker and could deliver insight into the disease process. This chapter addresses the recent discoveries on circulating microRNA and long non-coding RNA as diagnostic or prognostic biomarkers in colorectal cancer.

Keywords: Biomarkers; Colorectal cancer; Diagnostics; MicroRNA; Plasma; Serum.

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