An Overview of Concentrated Insulin Products
- PMID: 27574366
- PMCID: PMC5001226
- DOI: 10.2337/diaspect.29.3.136
An Overview of Concentrated Insulin Products
Abstract
IN BRIEF This article provides a summary of the use of available concentrated insulins in the outpatient treatment of patients with diabetes. Concentrated insulins work through the same mechanisms as other insulin products. They vary from each other in concentrations and pharmacokinetic/pharmacodynamics profiles but are each similar to their U-100 concentration counterparts. Patient education is important to minimize errors and the risk of hypoglycemia when using these insulin formulations.
References
-
- American Diabetes Association Classification and diagnosis of diabetes. Sec. 2 in Standards of Medical Care in Diabetes—2016. Diabetes Care 2016;39(Suppl. 1):S13–S22 - PubMed
-
- Bauters C, Ennezat PV, Tricot O, et al. .; REVE Investigators . Stress hyperglycaemia is an independent predictor of left ventricular remodelling after first anterior myocardial infarction in non-diabetic patients. Eur Heart J 2007:28:546–552 - PubMed
-
- Segal AR, Brunner JE, Burch FT, Jackson JA. Use of concentrated insulin human regular (U-500) for patients with diabetes. Am J Health Syst Pharm 2010;67:1526–1535 - PubMed
-
- Toujeo [package insert]. Bridgewater, N.J., Sanofi-Aventis, 2015. Available from http://products.sanofi.us/toujeo/toujeo.pdf. Accessed 18 May 2016
-
- Yki-Järvinen H, Bergenstal R, Sieman M, et al. .; EDITION 2 Study Investigators . New insulin glargine 300 units/mL versus glargine 100 units/mL in people with type 2 diabetes using oral agents and basal insulin: glucose control and hypoglycemia in a 6-month randomized controlled trial (EDITION 2). Diabetes Care 2014;37:3235–3243 - PubMed
LinkOut - more resources
Full Text Sources
Other Literature Sources
