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Review
. 2015 Sep 30:3:18.
doi: 10.1186/s41038-015-0017-5. eCollection 2015.

Tissue engineering in burn scar reconstruction

Ppm van Zuijlen  1 , Klm Gardien  2 , Meh Jaspers  1 , E J Bos  3 , D C Baas  4 , Ajm van Trier  5 , E Middelkoop  2
Affiliations
Review

Tissue engineering in burn scar reconstruction

Ppm van Zuijlen et al. Burns Trauma. .

Abstract

Nowadays, most patients with severe burns will survive their injury. This evolution is accompanied by the challenge to cover a large percentage of total body surface area burned. Consequently, more and more patients have to deal with the sequelae of burn scars and require (multiple) reconstructions. This review provides a gross overview of developments in the field of tissue engineering for permanent burn wound coverage and reconstructive burn surgery, focusing on usage and clinical effectiveness. Not only skin substitutes will be discussed but also the replacement of subcutaneous fat tissue and cartilage.

Keywords: Burns; Cartilage; Contracture; Reconstruction; Scar; Subcutaneous fat tissue; Substitute; Tissue engineering.

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