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Comment
. 2016 Oct;90(4):718-21.
doi: 10.1016/j.kint.2016.07.006. Epub 2016 Aug 26.

Timing is everything? Reconciling the results of recent trials in acute kidney injury

Christina M Wyatt  1 , Steven G Coca  2
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Comment

Timing is everything? Reconciling the results of recent trials in acute kidney injury

Christina M Wyatt et al. Kidney Int. 2016 Oct.
Free article

Abstract

Observational studies have failed to establish the optimal timing of renal replacement therapy in critically ill adults with acute kidney injury, with some studies suggesting benefit and others suggesting the potential for harm with earlier initiation. Two recent randomized trials have addressed this controversy, also with conflicting results. Careful consideration of differences between the 2 studies is essential when applying the results to clinical practice in the intensive care unit.

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