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. 2016 May;5(2):124-32.

Use of Platelet Rich Plasma and Hyaluronic Acid in the Treatment of Complications of Achilles Tendon Reconstruction

Pietro Gentile  1 , Barbara De Angelis  1 , Annarita Agovino  1 , Fabrizio Orlandi  1 , Alessandra Migner  1 , Camilla Di Pasquali  1 , Valerio Cervelli  1
Affiliations

Use of Platelet Rich Plasma and Hyaluronic Acid in the Treatment of Complications of Achilles Tendon Reconstruction

Pietro Gentile et al. World J Plast Surg. 2016 May.

Abstract

Background: The platelet-rich plasma (PRP) and hyaluronic acid (HA) constitute a system of tissue growth that can regenerate damaged tissue. This study was performed to evaluate the effect of PRP and HA in treatment of complications of Achilles tendon reconstruction.

Methods: We selected ten patients affected by Achilles tendon injuries resulting from post-surgical complications subsequent to tenorrhaphy and have treated them with autologous PRP in combination with HA to evaluate the improvement of lesions with wound closure.

Results: The treatment with PRP and HA for post-surgical complications of Achilles tendon was effective in healing and regeneration of soft and hard tissues. The healing time was shortened, and the treated area preserved a satisfying strength in plantar flexion and extension of the ankle, denoting to a decisive improvement in texture and a more rapid healing and a good cutaneous elasticity, with a significant reduction of the costs of hospitalization and the pain already the immediate postoperatively. The functional rehabilitation in terms of deambulation and joint mobility was complete.

Conclusion: The treatment we proposed allowed an easier and more rapid wound closure with excellent aesthetic improvement. Furthermore, the minimally invasive technique is well tolerated by patients.

Keywords: Achilles tendon; Hyaluronic acid; Platelet rich plasma; Reconstruction.

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Figures

Fig. 1
Fig. 1
A) pre-operative situation with detail of tendon rupture; B) intra-operative situation during tenorraphy; C) intra-operative situation during tenorraphy in detail; D) suture completed
Fig. 2
Fig. 2
A) pre-operative situation after tendon reconstruction following tenorraphy; B) pre-operative situation with detail of wound dehiscence, and exposition of sutures; C) pre-operative situation with diameter of wound dehiscence; D) pre-operative situation with diameter of wound dehiscence
Fig. 3
Fig. 3
A) intra-operative situation during sutures removal; B) intra-operative situation with detail of sutures removed; C) intra-operative situation with detail of sutures removed; D) post-operative situation after 10 days from the treatment based on sutures removal and reconstruction of damaged soft tissue
Fig. 4
Fig. 4
A) intra-operative situation during PRP infiltration in the bed of the ulcers; B) post-operative situation after 15 days; C) post-operative situation after 30 days; D) post-operative situation after 45 days from the treatment with completely wound healing
Fig. 5
Fig. 5
Box plot of the score used to assess the status of wounds as described in the materials and methods section (wide line represents the median, the grey box the scores between 25th and 75th percentile, the vertical bars include all the samples, with the exception of the scores accounted as outliers and plotted as circles
See this image and copyright information in PMC

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