Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2016 Dec;15(23):3159-3160.
doi: 10.1080/15384101.2016.1220720. Epub 2016 Aug 11.

ER-mitochondria contacts find their FATE

Mabrouka Doghman-Bouguerra  1   2   3   4 , Enzo Lalli  1   2   3   4
Affiliations
Editorial

ER-mitochondria contacts find their FATE

Mabrouka Doghman-Bouguerra et al. Cell Cycle. 2016 Dec.
No abstract available

Keywords: apoptosis; calcium; cancer-testis antigens; cell death; endoplasmic reticulum; mitochondria; transcriptional regulation.

PubMed Disclaimer

Figures

Figure 1.
Figure 1.
Diagram showing the action of FATE1 to increase ER–mitochondria distance and consequently decrease mitochondrial Ca2+ influx and apoptosis. ER, endoplasmic reticulum; MAM, mitochondria-associated membranes.
See this image and copyright information in PMC

Comment on

  • doi: 10.1016/j.devcel.2016.04.018

References

    1. Sbiera S, Schmull S, Assie G, Voelker H-U, Kraus L, Beyer M, Ragazzon B, Beuschlein F, Willenberg HS, Hahner S, et al. High diagnostic and prognostic value of steroidogenic factor-1 expression in adrenal tumors.. J Clin Endocrinol Metab 2010; 95:E161-171; PMID:20660055; http://dx.doi.org/10.1210/jc.2010-0653 - DOI - PubMed
    1. Doghman M, Karpova T, Rodrigues GA, Arhatte M, De Moura J, Cavalli LR, Virolle V, Barbry P, Zambetti GP, Figueiredo BC, et al. Increased steroidogenic factor-1 dosage triggers adrenocortical cell proliferation and cancer.. Mol Endocrinol 2007; 21:2968-2987; PMID:17761949; http://dx.doi.org/10.1210/me.2007-0120 - DOI - PubMed
    1. Doghman M, Figueiredo BC, Volante M, Papotti M, Lalli E. Integrative analysis of SF-1 transcription factor dosage impact on genome-wide binding and gene expression regulation.. Nucl Acids Res 2013; 41:8896-8907; PMID:23907384; http://dx.doi.org/10.1093/nar/gkt658 - DOI - PMC - PubMed
    1. Doghman-Bouguerra M, Granatiero V, Sbiera S, Sbiera I, Lacas-Gervais S, Brau F, Fassnacht M, Rizzuto R, Lalli E. FATE1 antagonizes calcium− and drug− induced apoptosis by uncoupling ER and mitochondria. EMBO Rep 2016; PMID:27402544; http://dx.doi.org/10.15252/embr.201541504 - DOI - PMC - PubMed
    1. Simpson AJG, Caballero OL, Jungbluth A, Chen Y-T, Old LJ. Cancer/testis antigens, gametogenesis and cancer.. Nat Rev Cancer 2005; 5:615-625; PMID:16034368; http://dx.doi.org/10.1038/nrc1669 - DOI - PubMed

Publication types

LinkOut - more resources